Time Machine "The backup was not performed …" error

I just started getting a Time Machine error when backing up my Macintosh Mini (mid-2010) running "Snow Leopard" OSX 10.6.8. I get a charmingly cryptic error:

The backup was not performed because an error occurred while copying files to the backup disk.

The problem may be temporary. Try again later to back up. If the problem persists, use Disk Utility to repair your backup disk.

Well I tried repairing the backup drive to no avail. I'm now repairing disk permissions on my main hard drive. But what did help is a Dashboard Widget called Time Machine Buddy. If you run it as an administrator, you can view the backup log and see which file it's having a problem with. To be honest, I have no idea why it is suddenly taking issue with a number of files, but it is.

Upon further investigation, I'm getting an "Error -36" reading the file. This is not good—according to Apple's Common System Error Messages page:

This file is having difficulty while either reading from the drive or writing to the drive. The file may have been improperly written data to the drive or the hard drive or disk may be damaged. This is almost always indicative of a media error (hard error on the disk). Sometimes (rarely) it is transient.

Definitely not good … I guess I'll need to get a new main hard drive. I should be less surprised than I am: I bought the machine in September, 2010, so given how quickly things go bad, 5 years shouldn't be such a surprise. What a pain, though … I'm not looking forward to this.

Update 2015-Dec-3:

I noticed Time Machine started having issues with external drives as well which didn't jibe with a failing system drive. I found another suggestion to do a "full reset" on Time Machine. I shortened the procedure to:

1. In System Preferences:Time Machine, click Options and remove any drives you can (certain drives are permanently added.) Then turn Time Machine "Off" and quit System Preferences.
2. Eject the backup drive and power it off.
3. Delete /Library/Preferences/com.apple.TimeMachine.plist. You'll need to have administrator privileges to do this.
4. Mount the backup drive, reset any optional exclusions in the Time Machine preferences then start a backup.

I don't know if this will fix my problems—one thing I forgot to do was to repair the external disks (especially those causing problems.)

And another thing: if you don't want to use Time Machine Buddy, you can also review the system.log in the Console app. Again, you'll need administrator privileges to see the file, but you can type "backupd" in the search (actually "filter") box and review what Time Machine—a.k.a. backupd—is doing. I found this more useful than Time Machine Buddy for hardcore debugging—TMB is good to have if you've got an occasional problem and want to take a quick peek at what's up.

I also noticed an error concerning being unable to parse the SystemMigration.log. I found it in Console and it was from when I installed the system software 5 years ago so I deleted it. I'm also running a Disk Utility Repair on all the external drives.

Update 2016-Nov-30:

Almost a year later and I think I may have found a more substantial solution! After another similar failure, I tried switching my backups to use Carbon Copy Cloner from Bombich Software. It's much less integrated than Time Machine, but—after several days of failures—I figured I would at least I would have some semblance of a backup. However, it started giving me messages about filesystem errors, and among their suggestions was one to check the signal connections.

I hadn't thought about this since the days of SCSI, when a poorly constructed cable or a bad enclosure or device, along with minor environmental changes like humidity, temperature, or the phase of the moon would suddenly cause system instability. Having a chain of more than a couple devices, weaving between 25-pin, 50-pin, and 68-pin standards, and deciding whether active or passive termination was the right choice was a nightmare—and all without any diagnostics other than drives failing to mount or disappearing or getting corrupted.

USB seemed to fix all that, but its improvements come at a cost hidden. USB is a far more resilient when it comes to poor connections, but once a certain threshold is crossed, the connection becomes, well, wonky. It's a bit like how digital TV fixed all of analog TV's picture distortion … until the signal gets so poor that digital just quits (although at that point analog is again preferable since it maintained picture—a very noisy picture—but at least it continued to work.)

Anyway, the tl;dr version is to try taking apart your whole USB chain and all the hubs. Install the more critical backup drives closer (fewer hubs) to the computer. Blow dust out of connectors. Once you get the signal integrity improved enough, all the problems seem to go away.